PURPA, EPAct 1992, and EPAct 2005, EISA 2007 (Continued) - August 27, 2008
The basic concepts underlying the economic regulation of energy. In addition, discussion, of three federal acts that form reference points for our national conversation about renewable energy.
What is CRISPR-Cas9 and how does it work? How do we edit genes? Jennifer Doudna, biochemist at UC Berkeley, explains.
The gene editing technique, created by UC Berkeley biochemist Jennifer Doudna and her colleague, Emmanuelle Charpentier, director of the Max Planck Institute of Infection Biology in Berlin, has taken the research and clinical communities by storm as an easy and cheap way to make precise changes in DNA in order to disable genes, correct genetic disorders or insert mutated genes into animals to create models of human disease.
CRISPR-Cas9 is a hybrid of protein and RNA – the cousin to DNA – that functions as an efficient search-and-snip system in bacteria. It arose as a way to recognize and kill viruses, but Doudna and Charpentier realized that it could also work well in other cells, including humans, to facilitate genome editing. The Cas9 protein, obtained from the bacteria Streptococcus pyogenes, functions together with a “guide” RNA that targets a complementary 20-nucleotide stretch of DNA. Once the RNA identifies a sequence matching these nucleotides, Cas9 cuts the double-stranded DNA helix.
Read more about CRISPR: http://news.berkeley.edu/2015/11/12/crispr-cas9-gene-editing-check-three-times-cut-once/
Video by Roxanne Makasdjian and Stephen McNally
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Bio Engineering/ME C117: Structural Aspects of Biomaterials - Professor Lisa Pruitt
This course provides an overview of medical devices, ... all » FDA regulatory issues, biocompatibility and sterilization technology. It examines biomechanical properties: isotropy/anisotropy, stiffness, bending stresses, contact stresses, multiaxial loading, plasticity, fatigue, fracture, wear, corrosion, design issues. Also covered: Orthopedics, Dental, Cardiovascular, and Soft Tissue Reconstruction.
Professor Pruitt's current research is focused on fatigue and fracture micromechanisms, cyclic damage zones, and evolution of structure due to cyclic loading and environment in advanced polymers and biomaterials;...
Video by Howard Hughes Medical Institute
http://www.hhmi.org
Full story: http://news.berkeley.edu/2015/09/09/viral-protein-causes-dengue-shock
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eCHEM 1A: Online General Chemistry
College of Chemistry, University of California, Berkeley
http://chemistry.berkeley.edu/echem1a
Curriculum and ChemQuizzes developed by Dr. Mark Kubinec and Professor Alexander Pines
Chemical Demonstrations by Lonnie Martin
Video Production by Jon Schainker and Scott Vento
Developed with the support of The Camille & Henry Dreyfus Foundation