UC Berkeley Chancellor Robert Birgeneau asks the campus community to pause for a minute on Memorial Day, May 28, 2011, at 3:00 pm, to remember those who sacrificed their lives in services of this nation. http://www.berkeley.edu/
The advent of high-throughput genome sequence analysis has enabled systematic discovery of somatic genome alterations through genome, exome, and transcriptome sequencing of paired human cancer and germline nucleic acids. These discoveries have led to the identification of somatic genome alterations in new pathways including epigenetic regulators, RNA splicing factors, and immune response regulators, in addition to previously known signal transduction, cell cycle, and transcriptional pathways. I will discuss alterations in these pathways by copy number disruption, mutation, and re-arrangement, especially as seen through the lens of recent and ongoing large- scale studies of lung adenocarcinoma and squamous cell lung carcinoma genomes, from The Cancer Genome Atlas and beyond—and will discuss the implications for the understanding of cancer pathogenesis and for the development of targeted and im- munomodulatory therapies.
Alert action by two members of the UC Berkeley police force played a key role in the arrest of kidnapping suspect Phillip Garrido and the return of Jaycee Lee Dugard, who in 1991 at age 11 was abducted from her South Lake Tahoe neighborhood. Lisa Campbell, manager of the UCPD special-events unit and Officer Ally Jacobs discuss the events leading up to the Garrido arrest.
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