The Cas9 enzyme must flex and bend in order to bind to the guide RNA (orange). Once the Cas9-RNA complex finds its target DNA (red), the cutting region of Cas9 (yellow) will swing into place relative to its mate (blue) only when the RNA and DNA correctly match. Only then does the enzyme cut the double-stranded DNA. Samuel Sternberg video http://www.berkeley.edu http://www.facebook.com/UCBerkeley http://twitter.com/UCBerkeley http://instagram.com/ucberkeleyofficial https://plus.google.com/+berkeley

European Civilization from the Renaissance to the Present

Computer Science 61B, 002 - Spring 2015 Data Structures - Joshua A. Hug Creative Commons 3.0: Attribution-NonCommercial-NoDerivs

The Responsible Conduct of Research Seminar Series gives graduate students, postdoctoral scholars, faculty, and staff the knowledge and tools to guide them through the increasingly complex ethical issues that they will face during their careers. Topical experts lead each session, using case studies and leaving time for Q&A. Monday, September 12 Conflict of Interest Jyl Baldwin, Research Administration and Compliance Office Attendees who participate in at least 8 of 12 sessions will receive a Certificate of Completion at the end of the year (the Spring Semester Schedule is TBA). Sponsored by the UC Berkeley Vice Chancellor for Research, Research Enterprise Services (RES), California Institute for Quantitative Biosciences (QB3), and the Center for Computational Biology (CCB). ...